Energy Drink Safety from 3 Different Food Science Lenses [YouTube]

How can we talk about the safety of energy drinks in the context of food science? How do Food Packaging, Food Chemistry, and Food Microbiology all impact the safety of a caffeinated beverage?
The following is a presentation given by GreenEyedGuide for the Food Science and Consumer Studies department at California State University – Long Beach in March 2018.


[1] Hello everyone and thank you so much for having me today. Who here likes coffee? Who here likes prizes? Great, because today I’m talking about caffeine in general. Statistically, only 10% of you in here are energy drink consumers, most of you like coffee. So even if you don’t like energy drinks, I encourage you to think of questions and play along with the pop quizzes I have in here, because if you do, you’ll get a prize. Even if you guess wrong, you’ll get a prize. Even if people laugh at your question or you ask a question other people know the answer to, you’ll get a prize. Why? Because we’re scientists, and science is nothing if not the pursuit of questions, right? And if you don’t want to ask your question out loud, you can write your question anonymously on one of these sheets of paper and I’ll answer it that way – but no prize for you.

Okay, here we go!

[2] Think of the last time you woke up EXHAUSTED. Any new parents in here, perhaps? Any Ph.D. students? Regardless, we’ve all had those days. Your alarm goes off, you start moving around and you feel it. In your eyes, all over your body – you’re exhausted! And right then and there, part of you knows that this day is going to be awful because your day is just getting started.

This was my life throughout high school.

I was a straight-A student with all honors and advanced placement classes. I did gymnastics 20 hours a week and competed nation-wide. I helped my mom (a single working mom) take care of my 3 siblings. I constantly got 5 hours of sleep or less and fell asleep in class.

That doesn’t sound THAT special, we all struggle to balance our commitments in life, but at that time, when I was in high school, Starbucks didn’t exist. Energy drinks didn’t exist. Coffee wasn’t cool, it was for old people like college students. If you wanted caffeine you drank Mountain Dew.

A wondrous thing happened when I decided to mashup my love for nutrition and chemistry and became a Biochem major – that was the same year Monster Energy was invented. Anyone know what year that was? (I’m revealing my age but I don’t care) While people everywhere were asking questions and trying these new “energy drink” things, I was learning about the ingredients and what they do in my classes. I was fascinated from the very beginning, and I’ve never stopped studying them.

[3] The reason I find energy drinks so fascinating is that they are not one product, like studying coffee, or tea or milk – caffeinated beverages lie on a spectrum. When people talk about energy drinks, they’re usually talking about a very narrow band on this spectrum which creates a few complications. And when I say complications, I mean – things I get to geek out over:

1)How do you create an effective energy drink ban when this Starbucks Doubleshot has the same main ingredients as the wannabe coffees from Rockstar and Monster?

2)How do we use reports of hospitalizations involving energy drinks if we don’t know what brand of energy drink?

3)How can we as food scientists come up with a caffeinated beverage for people who don’t like the taste of plain coffee or tea and want a portable ready to drink source of caffeine that isn’t going to kill them?

[4] The Science of Energy Drinks is a pretty broad topic, and I could talk for hours. I could, and I have written a book about energy drinks because I have so much to say. But let’s narrow our focus to some of the IFT Core Sciences. Where are my future packaging engineers in here? Let’s start with caffeine safety and food packaging.

[5] I’m going to ask you for permission to combine packaging with serving size and servings per container. This isn’t really the same as food packaging and food grade films, etc., but for the moment, let’s talk about how food is packaged when we say “food packaging”.

Here we have a jumbo muffin, multivitamins that look like candy, a bottle of Patron, and a steak. At what point does the packaging change whether or not something is healthy? What happens when a muffin is packaged in a way where the consumer is going to eat the whole thing and it turns out that one muffin was 6 servings? What happens when a vitamin looks so good and has cartoons on the bottle so that a kid wants to eat a whole bunch of them?

[6] This same question applies to caffeinated drinks too. At what point does the way something is packaged affect its safety? To answer that, we need to know more about caffeine consumption.

[7] POP QUIZ!!!

Does anyone want to guess how much caffeine you’re allowed to have a day if you’re under 18?

The American Academy of Pediatrics says those under 18 should avoid caffeine but since it’s in chocolate and soda, they should not consume more than 100 milligrams of caffeine a day.

Does anyone want to guess how much caffeine you can have per day if you’re a healthy adult? Several organizations, including Health Canada, the EFSA, and the FDA agree 400 milligrams is the max.

So right away we see the caffeine crisis in America isn’t as bad as one might think. We’re actually don’t ok – I’m sure there are some people who are outliers, but as a population in general, we’re doing okay.

This graph is the most accurate representation we have for Caffeine Consumption, from any source, excluding medication, in the US.

This figure comes from a study published in 2012. When I read it, I loved it so much, I wrote an email to the author. She wrote me back – it was awesome.

In this study, they surveyed ~42,000 people from all age groups and demographics. They made sure their sample was representative of the US population. They asked people how much caffeine they consumed, and they did something no other study has ever done before or since.

When I read research articles about “Caffeine in the Military” they ask how many energy drinks did you consume. They don’t ask which ones, they don’t distinguish sports beverage from energy shot from coffee or tea.

In this study, they got specific. They got the specific brands and flavors of energy drinks, coffee, tea, energy shots, sports beverages, chocolate beverages. Then they used the Caffeine Informer database to calculate exactly how much caffeine was in that brand, that size, that flavor.

[8] If you have time, I highly recommend reading this paper – it gets so much better. They broke down how much caffeine each age group consumes a day, right, that’s what we saw on the last slide, but they also broke down how much caffeine comes from where. We can look at the biggest sources of caffeine for each age group, and how people change their caffeine habits over time.

[9] For example, here’s a look at how caffeine habits change from teen years to college years. For college-age people, soda is still the #1 contributor. And tea is still #2! But look at how much coffee has grown.

Energy drinks are still in last place! And these two age groups have the highest energy drink consumption across the whole age range. It never gets better (or worse?) than 10% of the age group.

[10] But back to our point here about caffeine and packaging – when we talk about caffeine safety, we absolutely have to talk about serving size, servings per container, and Volumetrics, or energy density.

Here, by energy, I don’t mean the fuzzy “energy = lack of fatigue” terms we use to talk about energy drinks, and I’m not talking about physiological energy as ATP. Volumetrics normally means the number of Calories in a given unit. So here we’re talking about caffeine per oz.

Now that you know a healthy adult can only have 400 mg caffeine per day, you know that concentrated forms of caffeine can be inherently more dangerous. Take this Redline and this giant Monster can (technically 4 servings per container). If you’re the kind of person that has trouble nursing your caffeine, then the Redline is going to be inherently more dangerous than this big giant can.

With a hot coffee, it has built-in speed control. You can’t shotgun a coffee, that’s not how coffee works. Also, it’s usually too hot or too iced to chug. Since there’s physically more fluid, you have more time for that caffeine to kick in before you finish the whole thing. This is why I don’t like energy shots. If you’ve never had a shot before and don’t know your limits, you could take the shot, think, “Hmmm, I don’t feel it, I should take another one”…and then by the time the caffeine kicks in, it’s too late.

These are things we have to consider when we talk about caffeine safety.

[11] Let’s look at another IFT Core Science. Where are my future food chemists? This was my specialty – as a Biochem major, I learned a lot about how ingredients react in the body. I know how ingredients affect metabolism like fatty acid oxidation, glycolysis, etc. Sometimes this is too much biochem for some of my fellow food scientists, so for today, let’s talk about chemistry as in the reactions that happen in the food.

[12] When it comes to Food Chemistry and caffeine safety, the big question is this – when do safe ingredients become unsafe when combined? In other words, what is it about Monster that makes it more dangerous than a cup of coffee? What about if we compare it to this V8+Energy? What about this Starbucks drink that has added stereotypical energy drink ingredients such as taurine, guarana, and ginseng? How do we know where to draw that line and say a caffeinated beverage is not safe?

[13] Hey look, another pop quiz!

Assuming you drank the whole container, which drink has the most caffeine?

Surprising, right? The Starbucks coffee has way more than the Monster, and Also surprising that this juice-looking Bai drink has about the same amount of caffeine as Red Bull. If you want to ban energy drinks, how do you handle products like this V8?

The reason I’m showing you these amounts is there are two conflicting proposals:

1)Energy drinks are dangerous because of the high amounts of caffeine;

2)Energy drinks are more dangerous than coffee because of ingredient interactions.

It looks like the first theory (the high amounts of caffeine) isn’t inherently true. Anytime there’s a news article about energy drinks, what brands do they show? Red Bull, Monster, and Rockstar – the big three. But we can see Red Bull is “weak sauce” compared to Monster and this coffee.

What about the second theory, the one about ingredient interactions?

[14]. Do Ingredient Interactions make energy drinks more dangerous than coffee? Yes, for three reasons:

1)Energy drinks are sometimes combined with alcohol, which has led to dangerous and high levels of blood alcohol contents. Normally, when you’ve had too much to drink, you pass out. Your body literally prevents you from drinking more alcohol by putting you to sleep. But what if you didn’t fall asleep? Then you’d stay awake long enough to drink that much more alcohol.

2)This isn’t really an ingredient interaction but energy drinks can contain multiple sources of caffeine: caffeine, guarana, yerba mate, guayusa, green tea extract… These different forms of caffeine aren’t interacting with each other, but they are all increasing the total amount of caffeine you are consuming, and that’s the dangerous part – the total caffeine consumption. When energy drinks first came out, they were not disclosing the total amount of caffeine from all sources. Red Bull paved the way for this labeling, and other energy drinks (though still not all of them) follow suit.

3)Getting caffeine from a carbonated source it will feel stronger than if you got the same amount of caffeine without the carbonation. You know how people get tipsy faster off champagne than beer? The bubbles irritate the stomach lining slightly, and caffeine and alcohol are two substances which are absorbed in the stomach – everything else has to wait till it gets to the small intestine.

By a show of hands, did anyone feel like something is missing from this list? Among the reasons I mentioned why energy drinks ARE more dangerous, I did not mention heart arrthymias.

[15] Last year, a teen in South Carolina died from a caffeine overdose. Among the things he drank that day:

  • Mountain Dew
  • McDonald’s latte
  • Undisclosed energy drink

The energy drink was the last thing he consumed. We don’t know how much caffeine was in that drink, or what other ingredients were in it. Which means we can’t talk about ingredient interactions. We’re missing some critical data, but several news articles that reported his death referred to this article published in the Journal of the American Heart Association. According to the press, this research article found, “energy drink consumers could be at higher risk of abnormal heart beats and dangerous changes in blood pressure.”

Unfortunately, the scientists who wrote this paper would disagree with that statement.

[16] This study was randomized, double-blind, placebo-controlled, but they only used 18 people in their mid-20s. That’s not a big sample size, but the other big problem is that they used 320 mg caffeine. The EFSA says you can have how much per day? (400 mg), and only 200 mg at a time. So this is more caffeine than you’re supposed to have at a time.

In this study, there was no difference in heart rate or blood pressure between the two groups at any time. The did find a small but statistically different change in something called a QTc, but even the authors are saying this shouldn’t be alarming and that the risk may be negligible.

Where does that leave us in our big question on ingredient interactions?

[17]. Do Ingredient Interactions make energy drinks more dangerous than coffee? No, for three reasons:

1.A review of multiple studies on the effects of caffeine on heart arrhythmias found moderate caffeine is okay for people with heart arrhythmias. There is no scientific evidence that caffeine causes heart arrhythmias in those with a healthy heart. Nor is there any evidence that drinking caffeinated beverages long-term will cause an arrhythmia to develop. However, some people could be unaware that they have an arrhythmia or that they are prone to developing one based on their genetics, which is why caffeine should always be consumed in moderation.

  1. The EFSA determined it’s unlikely there is any interaction between caffeine, taurine, and glucuronolactone.
  1. Many energy drinks feature caffeine, B-vitamins, and a bunch of other ingredients which aren’t in large enough doses to do anything, physiologically.

[18] When it comes to food chemistry and caffeine safety, at this point, we have more evidence that there are NO interactions in energy drinks than evidence to the contrary. This question may be impossible to answer as new energy drinks come out with different combinations of ingredients. In order to challenge or improve our understanding of ingredient interactions, we shouldn’t talk about people who get sick from energy drinks without talking about the total caffeine content or the other ingredients present.

[19] Let’s talk about one more IFT Core Science before we wrap up. Are there any future food microbiologists in here?

[20] Food Micro was never my favorite part of food science. I know enough to geek out when the CDC publishes their report on foodborne illness outbreaks, and when food has been in the “temperature danger zone” too long… but I still struggle with which food preservatives inhibit yeast and mold or what to use when the water activity and pH are high enough for your drink to become a hospitable environment for undesirable microbes.

But there are two things I can tell you two things that you should remember:

1)I’ve been on the Quality Audit team for almost 5 years – it was my job to review specifications of ingredients suppliers, review audit reports, review food micro testing regimens and HACCP plans and flow charts and testing results and use all that information to complete a risk assessment for that ingredient. I’ve seen things that scare me. I’ve read audit reports that make me glad I didn’t have time to eat lunch. I’ve talked to ingredient suppliers who clearly have no idea what they’re doing, and some who are even reluctant to test because “this is what we’ve always done”.

2)Red Bull has been more transparent than any other energy drink brand in opening up their facility and inviting inspections of their manufacturing and advertising practices. I trust Red Bull’s manufacturing more than Monster or Rockstar and WAY more than some of the “natural energy” drinks I see that are only sold online.

With all supplements, in fact, with all online food and supplements, I encourage consumers to look for red flags, to exercise caution. Natural doesn’t always mean safe.

[21] If I had to boil down all my research, all my thoughts about caffeinated beverages, it would come down to two phrases:

1)Not All Energy Drinks – There are SO many caffeine-containing drinks out there that look nothing like their energy drink forefathers. Generalizing energy drinks is like calling sandals, Uggs, and stilettos all “shoes”. Some of them are functional and convenient, some of them are all looks no function, some will hurt you the moment you try them if you don’t know what you’re in for

2)The best way to approach caffeine safety is through the 5 Levels of Fatigue

[22] With this system I have helped bartenders cut back from 4 Monsters a day to half a can a day. I have helped my family, friends, and strangers on the internet avoid caffeine toxicity, dependence, and tolerance.

Here’s how it works:

[23] At Fatigue Level 0, you need no caffeine – you’re feeling great, awake, alert, alive. Maybe you just aced a final. Maybe that person you’ve been crushing on smiled at you. Maybe your favorite team just made the playoffs. This is your baseline.

[24] Fatigue Level 1. Dehydration causes fatigue. If you’re feeling tired, whether it’s 5 in the morning or 3 in the afternoon, your first task is to drink water.

It doesn’t have to be plain water. Put some cucumbers in it, get carbonated water, add regular MIO, whatever, just don’t reach for caffeine. Not yet.

[25] Fatigue Level 2. At this point, you have ruled out dehydration. Time to get some help. There are plenty of energy drinks with less than 100 mg per container, and with caffeine from a natural source. Here are some of my favorite examples.

For best results, you’re looking for something with natural caffeine, something NON-carbonated, and something with no sugar. You can put plain black coffee in this level, just watch your serving size (think small/tall, not Grande).

Carbonation and sugar do not belong in Fatigue Level 2.

[26] Fatigue Level 3. Struggle City, population = you.

For best results, do not exceed 200 mg. That’s the limit for a single serving anyways.

You STILL don’t want anything carbonated – not yet.

Instead of carbonation, look for something with at least some juice content. That juice should give you a teeny bit of sugar, and drinks with juice are almost never carbonated. We don’t want carbonation yet.

[27] Fatigue Level 4. out of 5. This is it. This is “Fall Asleep Standing” mode. This is “need to pull an all-nighter” or double-shift time.

Do. Not. Consume Fatigue Level 4 on a daily basis. Why? Because this is for emergencies only. What would happen if you had a fire drill at your school or work every day? You’d start ignoring it. And so it goes if you have this much caffeine every day. If you want the caffeine to work, you must not consume this caffeine on a regular basis.

Because it’s an emergency, it’s okay to go above the 200 mg – at – a time limit. This is also the point where we introduce carbonation. Why? Caffeine gets in through the stomach, and when there’s carbonation involved, it gets in that much easier.

So if you had two energy drinks, each with 100 mg caffeine – the carbonated one is going to feel stronger. This is why the 5 levels of fatigue is a scale. There are incremental increases based on ingredients like sugar and caffeine.

[28] Level 5 is sleep. There comes a point where no amount of caffeine can save you. There comes a point where you must give in and get some rest. When you hear stories about people who can drink coffee right before bed or fall asleep while drinking an energy drink, either they have a genetic polymorphism where they can metabolize caffeine so quickly that it doesn’t affect them, OR it’s because they have reached their limit. It’s extremely difficult to ask for help, to accept our limitations. But if we’re going to stay healthy, we have to acknowledge when we reach that point.

[29] I am on a quest to learn as much as I can to help me answer the question, “Are energy drinks safe?” If you would like to learn more about some of the caffeinated drinks I’ve mentioned today, some of the research I’ve cited my book, a particular ingredient, please save this page in your favorites and let’s connect on social media.

[30] Thank you all. Who has questions?


Energy Drinks Causing Holes in the Brain? Energy Drinks in the News

In October 2017 a news story surfaced that a man suffered a severe brain injury because of excessive consumption of energy drinks. Biochemist and Energy Drink Guide author GreenEyedGuide explains what consumers should take away from this news story.

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Bai Sparkling, Cocaine Energy, and Monster Ultra Violet: July Recap of Quick Reviews – Science of Energy Drinks

Here’s a recap of the quick reviews posted this month for the “Science of Energy Drinks” series on the GreenEyedGuide Instagram and Facebook pages: Bai Sparkling Antioxidant Infusion, Cocaine Energy, and Monster Ultra Violet.

Read more

Consumption of Energy Drinks Among College Students in Quebec – Energy Drinks in the News (SPIN ALERT)

Turns out not a lot of college students in Quebec drink energy drinks, but watch out for how the news will spin concern about those who do.

Here’s the journal article (via capture because there’s no link to read the full thing):



This study involves over TEN THOUSAND college students across THIRTY-SIX different public colleges in Quebec.

Out of the 10,283 people who participated in the survey, only ~9.1% reported consuming an energy drink at least once a week in the previous month.

This means 9,348 out of 10,283 college students surveyed do not have an energy drink every week (like, zero energy drinks at all? For the whole week? In college?)



Because this is college, the study also looked at alcohol consumption and use of cannabis, glues/solvents, and amphetamines.

FACT – Mixing energy drinks and alcohol is a baaaaaaaaadddd idea. This study properly suggests that combination of alcohol and energy drinks poses a risk for serious adverse effects. 

FALSE – Any statements like “college students who use energy drinks are more likely to abuse psychoactive substances…more likely to demonstrate excessive use of alcohol”

Approximately 1-in-4 people (247 out of 935, ~26%) who said they drink at least one energy drink said they also use psychoactive substances. This finding is not proof that energy drinks were a gateway to psychoactive substances for these people. How many people use psychoactive substances but not energy drinks?

There were even fewer people who reported consuming alcohol-energy drink combos (109 out of 935 people. 1.1%).

That means I have at least 109 more people to convince that this combo is a waste of booze (because you won’t feel it/can’t enjoy it) and a dangerous idea (because you won’t feel drunk, but you ARE in fact impaired).



The journal article conclusion reads

“A majority of respondents are not heavy users of ED (energy drinks), AED (alcohol+energy drinks), or ED with drugs.”

Can we just stop there and celebrate that for a minute before we give fodder to the “Energy Drinks are Poison” camp?

“Yet, the profiles of ED consumption potentially harmful to health that characterize some participants indicate that the potential health consequences of such behaviour are of concern.”

I am worried this last line will get translated as, “some participants who consume energy drinks exhibit behavior that is potentially harmful to health, so we should probably be worried about all energy drink consumers.”




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Beverages for Writers: Drinks to Boost Energy

The following is a guest post written by Bruce C. McAlister and edited by GreenEyedGuide. As a writer, Bruce shares the different options writers have when they need an energy boost, and highlights some of the benefits of energy drinks. 

Do writers need energy? Even if a writer is just sitting and typing most of the time, writing requires mental alertness and concentration. Just like any other person, writers need nourishment. However, with certain pressures, deadlines, and all-nighters, writers sometimes need an energy boost to keep them going. Since writers sit most of the time, eating more food is not such a sound option because they would most likely eat too much.

In effect, some writers rely on an energy boost from beverages, but they do not need to limit themselves to drinking coffee. There are several options to choose from. Consuming energy drink is one option, and there are a number of benefits that can help writers maintain the energy and focus they need while writing.

Energy Boosting Drinks for Writers:

  1. Coffee

This option is obvious. The caffeine in coffee helps improve focus, which is exactly what writers need. Plus, many people love coffee for its taste alone.

  1. Water

Writers need to stay hydrated. There are times when writers are in the zone and they don’t have the urge to get up and grab something to eat. At minimum, they should remember to drink some water. Dehydration can cause tiredness and loss of concentration.

  1. Green Tea

A cup of tea has less caffeine than a cup of coffee, but this is still enough caffeine for a boost of energy to help writers continue working on their composition. Tea also has antioxidants which provide several health benefits. Moreover, the boost from tea is less likely to cause the jitters than the boost from coffee.

  1. Orange Juice

According to health experts, flavonoids from fruits help pump-up the blood flow in the brain. This applies to flavonoids in orange juice as well. In effect, orange juice can increase mental energy needed to write.

  1. Yerba Mate Tea

This is a popular tea drink in Brazil, Uruguay, and Argentina. The beverage is concocted from the leaves of the yerba mate plant. It contains more caffeine than most tea variants. Additionally, it has B-vitamins, antioxidants, magnesium, and potassium. It enhances clarity, focus, and mental energy without the headaches and jitters that result from other caffeinated drinks.

  1. Energy Drinks

Energy drinks are not just supplements for extreme athletes. Energy drinks are also popular among students looking to boost their brain power when studying for exams. Writers can also benefit from energy drinks.

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Benefits of Energy Drinks for Writers

  1. Energy and Focus

Energy drinks make people feel more energetic, alert, awake, enthusiastic, and productive. Thanks to the caffeine content, this can help writers stay focused on their writing. With improved focus, some writers might feel energy drinks help them think more quickly.

  1. Standardized Caffeine Content

While the caffeine content of coffee and tea can vary drastically, caffeine from energy drinks is standardized and is normally declared on the label. Caffeine content in tea and coffee varies by brewing method, the quality of the beans and leaves used, and other factors. However, energy drinks have standardized recipes so the caffeine content in a bottle or can stays consistent. With this consistency, writers can determine exactly how much caffeine they will ingest.  As a result, they can then manage their intake more accurately, and avoid the negative effects of consuming too much caffeine.

  1. Convenience

Most energy drinks are served cold so it’s so possible to consume them more quickly than a cup of tea or coffee. While it is never recommended to “chug” an energy drink, the cold temperature can offer convenience for people who don’t have the time to prepare coffee or tea. Basically, energy drinks are ready to drink – no need to boil, heat, or brew.

  1. Flavor Variety

Energy drinks have a wide array of flavors to choose from. When writers start getting bored with the taste of tea or coffee, there are several flavor options from the wide variety of energy drinks. There are energy drinks that taste like soda, some that taste like coffee, some that taste like fruit juice, and some that taste unique.

  1. Additional Nutrients

Other than caffeine, energy drinks have additional nutrients that can help writers improve their writing game. These nutrients include B-vitamins, taurine, glucuronolactone, and ginseng. These nutrients come with their own benefits which can help writers get through all-nighters.

  1. Invigorating Taste

Many energy drinks are served cold and carbonated. Carbonation helps some people feel instant refreshment. On a hot day, some people will find a cold, carbonated energy drinks easier to consume than hot coffee mixed with milk or dairy.

  1. Calorie Free

For people trying to control their Calorie or Sugar intake, there are many Zero Calorie and Sugar-free energy drink options. For some people, these options might be more appealing than consuming coffee without cream and sugar.

Writer’s Choice

Writers have several options to boost their energy when they write. These beverages should be consumed in moderation since too much caffeine can be harmful. Writers should try these beverages when they find themselves struggling to stay focused, staring into nothingness, or consistently yawning. If you are a writer and find yourself struggling to finish your composition, which of these beverages will you choose?

Author Bio

Bruce McAlister Bruce C. McAlister is one of the proponents of . He is also a successful writer, social media strategist, and entrepreneur working as the marketing arm for their business. Bruce travels to help stop world hunger. He believes that 90% of world issues can be solved using proper communication. This is what inspires him to write.




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