What if I told you about gluco-neo-genesis and biotin- Book Excerpt of the Week

Gluconeogenesis literally means the creation of new glucose. This process is kind of a big deal because glucose is the primary source of fuel for our bodies and there are times we have to make that fuel ourselves (as opposed to ingesting it). That process of gluconeogenesis relies on enzymes, which are like tiny machines in our bodies that do the work to keep us functioning. Those enzymes/machines rely on the vitamin BIOTIN the way a remote control relies on batteries.

In general, BIOTIN-dependent enzymes are involved in the metabolism of carbohydrates, fats, and proteins BUT BIOTIN is REALLY BASIC and BORING in the role it plays. We’ll get to that next week…

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STAY TUNED every Monday (and sometimes Tuesday) for more book excerpts and the science behind energy drink ingredients as we continue our page-by-page exploration through the Energy Drink Guide.

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Thiamin and Carbohydrate Metabolism – Book Excerpt of the Week

Last week we talked about how some energy drinks have B-vitamins, but not all B-vitamins are relevant to the way the body generates energy. If the B-vitamins were the Avengers, then Thiamin would definitely be one of the strongest members. Thiamin is a crucial part of how the body turns glucose into energy.


Glucose is the most basic unit of a carbohydrate and the preferred fuel for the body. As a glucose molecule is broken down to release energy it must become a molecule/metabolite named pyruvate. Thiamin (as its coenzyme form, thiamin pyrophosphate or TPP) keeps that enzyme humming like a well-oiled machine. So without sufficient thiamin, carbohydrate metabolism screeches to a halt. Thiamin as TPP participates in the metabolism of fat, protein, and nucleic acids, but it’s carbohydrate metabolism that’s first to go haywire with a thiamin deficiency.

Stay tuned as we look at other B-vitamins in our page-by-page tour through my book on the science of energy drinks and their ingredients.

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